Heart Nutrition Coenzyme Q10 powder/Coenzyme Q10 capsules 10%98% Water soluble ester soluble

---Product Description---

Coenzyme Q10 (Coenzyme Q10, CoQ10), also known as Ubiquinone (UQ) and Coenzyme Q (CoQ), is a coenzyme present in all eukaryotic organisms that perform aerobic respiration. It is a benzoquinone fat-soluble compound with a structure similar to vitamin K. Q represents the quinone group, and 10 represents the number of isoprene attached to its tail. It is mainly formed in the inner membrane of mitochondria, and a small part can also be obtained through food, such as beef, eggs, oily fish, nuts, oranges, broccoli and other fruits and vegetables.

Coenzyme Q10 is widely distributed in the human body and exists in various organs, tissues, subcellular components and plasma, but its content varies greatly. The mass concentration is higher in tissues and organs such as the liver, heart, kidneys and pancreas. The main function is to drive human cells to produce energy. Coenzyme Q10 is mainly involved in the mitochondrial oxidative phosphorylation and ATP production process, regulates the cellular redox environment, carries reduced electrons into the vesicle or out of the cell during the electron membrane penetration process, and participates in the formation of the proton gradient of the inner membrane and plasma membrane. It can accelerate cell renewal and stimulate cell activity, thereby greatly promoting the ability of cells to absorb nutrients. Adding coenzyme Q10 ingredients to skin care products can effectively help skin cells actively absorb other nutrients in skin care products, and has health-preserving effects such as accelerating metabolism and slowing down aging.

As a health product, coenzyme Q10 has the functions of protecting the heart, enhancing energy, and improving immunity. It is suitable for athletes, high-intensity mental workers, and the stabilization and recovery of patients with heart disease, diabetes, etc.

Coenzyme Q10 is widely present in cell membranes, especially in mitochondrial membranes, and is mainly distributed in the heart, lungs, liver, kidneys, spleen, pancreas and adrenal glands. The whole body content of Coenzyme Q10 is only 500~1500mg, but it plays an important role. Coenzyme Q10 is relatively high in the heart, kidneys, liver and muscles. At the same time, 95% of Coenzyme Q10 in the human body exists in the form of ubiquinol (reduced Ubiquinol), but the brain and lungs are excluded. It is speculated that it may be due to the high oxidative stress in these two tissues, which oxidizes ubiquinol into oxidized ubiquinone (oxidized Ubiquinone).

With the increase of age, the content of Coenzyme Q10 in the human body will gradually decrease. Taking 20 years old as the standard line, at the age of 80, the natural attenuation of Coenzyme Q10 in various parts of the human body is: liver: 83.0%; kidney: 65.3%; lung: 51.7%; heart: 42.9%. Therefore, it is generally accepted that the heart is the organ that most needs coenzyme Q10 supplementation, or that many elderly heart discomforts come from a lack of coenzyme Q10.

---Product classification and Application---

1. Anti-aging
Coenzyme Q10 is an energy converter in cell mitochondria. It participates in the "Tricarboxylic acid cycle" by transferring and delivering electrons to produce ATP (adenosine triphosphate), an energy factor for cell metabolism. When humans are 20 years old, their ability to self-synthesize Coenzyme Q10 reaches its peak and is maintained until about 50 years old. [4] It will decrease year by year in the future because the mitochondrial DNA material of cells storing Coenzyme Q10 is damaged by oxygen free radicals, resulting in a decrease in independent synthesis of Coenzyme Q10. As a result, the metabolic function of human cells, especially heart cells, declines, and "aging" appears.
Experiments have shown that Coenzyme Q10 in the body plays an antioxidant role by directly reacting with peroxide free radicals after it is converted into the alcohol form. In vitro experiments have also found that the antioxidant coenzyme Q10 can protect mammalian cells from apoptosis caused by mitochondrial oxidative stress. Clinical studies have shown that oral coenzyme Q10 is effective in treating Parkinson's syndrome, Alzheimer's disease and other mitochondrial dysfunction and aging. Relevant neurodegenerative diseases have significant effects.
2. Anti-skin wrinkles and delay skin aging
Local experiments show that as age increases, the ability of skin collagen to resist damage from oxidative stimuli such as ultraviolet rays decreases. Long-term use of Coenzyme Q10 can effectively prevent skin photoaging and reduce wrinkles around the eyes, because Coenzyme Q10 can penetrate into the skin growth layer. Attenuates the oxidation reaction of photons. With the assistance of tocopherol, it can activate specific phosphorylated tyrosine kinase to prevent oxidative damage to DNA, inhibit the expression of collagenase in human skin fibroblasts under ultraviolet irradiation, and protect the skin from damage. Extensive research suggests that coenzyme Q10 inhibits lipid peroxidation, reduces the generation of free radicals, protects the SOD active center and its structure from free radical oxidative damage, increases the activity of SOD and other enzymes in the body, and inhibits apoptosis induced by oxidative stress. , has significant antioxidant and anti-aging effects.

3. Anti-fatigue
In the mid-1970s, Mitchell's chemiosmotic hypothesis revealed the energy conversion in organisms and the important role of coenzyme Q10 in the mitochondrial energy conversion system.
Coenzyme Q10 is a coenzyme for at least three mitochondrial enzymes (multi-enzyme complexes I, II and III). Its chemical structure is a 2,3-dimethoxy group with an isoprene side chain attached to the 6-position carbon. -5-Methyl-1,4-benzoquinone derivative. Its quinone ring plays the role of transferring electrons and protons in the oxidative respiratory chain. This role is key to the formation of ATP and is essential for all life forms. ATP is the main storage form of energy in the body and is also an important basis for the normal functioning of all cell functions. The biological activity of Coenzyme Q10 mainly comes from the redox properties of its quinone ring and the physical and chemical properties of its side chains. It is a natural antioxidant and cell metabolism initiator produced by the cells themselves. It can protect and restore the integrity of the biofilm structure and stabilize the membrane potential. It is a non-specific immune enhancer for the body, so it shows excellent anti-fatigue effects. It is a coenzyme Q10 keeps cells in a good and healthy state, so the body is full of vitality, energy and brainpower.
4. Muscle energy
Experiments show that CoQ10 greatly promotes heart health and that appropriate levels of CoQ10 in the body are necessary for proper muscle function. Biochemical analysis of muscle cell extracts found that when the concentration of coenzyme Q10 was lower than 20% of normal, the functional activities of mitochondrial complex I+II and complex I+III were severely reduced. Several studies have clearly shown that supplementation of 100-150 mg/day of CoQ10 can significantly improve the condition of people suffering from muscular dystrophy. Many overweight people have very low Coenzyme Q10 content, and supplementation can enable them to lose weight. This is because the role of Coenzyme Q10 can accelerate the metabolism of fat, making the limbs and brain more energetic and energetic.
5. Anti-tumor effect and immunomodulatory effect
Research in recent years has shown that coenzyme Q10 has anti-tumor effects and has certain clinical effects on late-stage metastatic cancer. It can prevent coronary heart disease, relieve periodontitis, treat duodenal ulcers and gastric ulcers, enhance human immunity and relieve symptoms. Significant effect on angina pectoris

Applicable groups
① Athletes, mental workers, and people with poor immunity will benefit from proper supplementation of coenzyme Q10;
② Supplementation of coenzyme Q10 will help improve the condition of patients with heart disease, periodontitis, gastrointestinal ulcers, Alzheimer's disease, and diabetes;
③ In addition to supplementing vitamin C, people with severe gingival bleeding can also take coenzyme Q10 to relieve symptoms.

---Certificate of Analysis---